MILTEFOSE 50 is a prescription medicine containing Miltefosine 50 mg, an orally active antiprotozoal drug primarily used for the treatment of leishmaniasis, a serious parasitic infection prevalent in certain parts of India and other tropical regions. Miltefosine represents a significant advancement in the management of leishmaniasis as it is one of the first effective oral therapies, offering an alternative to injectable treatments.
Miltefosine works by disrupting the cell membrane and metabolic processes of the parasite, leading to its elimination from the body. MILTEFOSE 50 is manufactured following stringent quality standards to ensure consistent efficacy, safety, and patient compliance. When used under proper medical supervision, it plays a crucial role in controlling and eliminating parasitic infections.
Uses
MILTEFOSE 50 is mainly indicated for the treatment of:
Visceral leishmaniasis (Kala-azar)
Cutaneous leishmaniasis
Mucocutaneous leishmaniasis, as recommended by a specialist
This medicine is particularly valuable in endemic regions and is used as part of national and international leishmaniasis control programs. The exact indication and treatment duration depend on the type of leishmaniasis and patient condition.
Benefits
MILTEFOSE 50 offers several important benefits in the management of parasitic infections:
Effective Oral Therapy: Eliminates the need for injections, improving patient comfort
High Efficacy Against Leishmania Parasites: Targets and destroys the parasite at the cellular level
Improves Treatment Compliance: Convenient oral dosing supports adherence
Reduces Disease Complications: Helps prevent progression and systemic involvement
Clinically Proven Medicine: Supported by extensive clinical studies and global use
Suitable for Program-Based Treatment: Widely used in public health initiatives
With proper use, MILTEFOSE 50 helps achieve complete parasite clearance and clinical recovery.
Dosage
The dosage of MILTEFOSE 50 is determined strictly by a healthcare professional based on body weight, age, and type of infection.
Adults: Usually 50 mg taken 23 times daily
Administration: Capsules should be swallowed whole with water, preferably after meals to reduce gastrointestinal discomfort
Duration: Treatment typically continues for 28 days or as prescribed
Missed Dose: Take as soon as remembered unless it is close to the next scheduled dose
Important: Complete the full course of treatment even if symptoms improve early. Do not stop the medicine without medical advice, as incomplete treatment may lead to relapse or resistance.
Side Effects
Like all medicines, MILTEFOSE 50 may cause side effects in some patients.
Common side effects include:
Nausea
Vomiting
Diarrhea
Abdominal pain
Less common but serious side effects:
Elevated liver enzymes
Kidney function changes
Severe dehydration due to persistent vomiting or diarrhea
Patients experiencing severe or prolonged side effects should seek medical attention immediately.
Precautions and Warning
Pregnancy: Miltefosine is contraindicated during pregnancy due to potential risk to the fetus. Effective contraception is required during treatment and for several months after completion
Breastfeeding: Not recommended while on treatment
Liver and Kidney Disease: Use with caution; regular monitoring is essential
Hydration: Adequate fluid intake is important to prevent dehydration
Drug Interactions: Inform your doctor about all medications being taken
This medicine should only be used under strict medical supervision.
Conclusion
MILTEFOSE 50 (Miltefosine 50 mg) is a highly effective oral antiprotozoal medication for the treatment of leishmaniasis. Its oral formulation, proven efficacy, and role in public health programs make it a valuable option in managing this potentially life-threatening disease.
When taken as prescribed and with appropriate monitoring, MILTEFOSE 50 helps achieve successful treatment outcomes and reduces disease burden. Patients must strictly follow medical advice, complete the full treatment course, and adhere to all precautions to ensure safe and effective therapy.




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