sitagliptin and metformin hydrochloride tablets

About sitagliptin and metformin hydrochloride tablets

ST-GLIPTIN M 100/500 is a combination oral antidiabetic medication formulated for the effective management of type 2 diabetes mellitus in adults. By combining two powerful agentsSitagliptin and Metformin Hydrochloridethis medication helps to improve blood glucose control alongside a balanced diet and regular exercise. It is particularly useful for patients whose blood sugar levels are not adequately controlled by metformin alone.

Key Ingredients:

Sitagliptin (100mg): A DPP-4 inhibitor that helps enhance the bodys own ability to lower elevated blood sugar levels by increasing incretin levels.
Metformin Hydrochloride (500mg): A biguanide class antidiabetic that reduces glucose production in the liver and improves insulin sensitivity.

Key Benefits:

• Helps to lower both fasting and postprandial (after meal) blood glucose levels.
• Improves glycemic control in adults with type 2 diabetes mellitus.
• Combines dual mechanisms of action for better diabetes management.
• Reduces the risk of diabetes-related complications when used long-term.
• May support slight weight reduction or prevent weight gain, unlike other diabetes medications.
• Offers a convenient single-pill option for patients needing combination therapy.

How Does It Work?

ST-GLIPTIN M 100/500 works through a synergistic action of its two active ingredients:

• Sitagliptin enhances the levels of incretin hormones, which stimulate insulin release from pancreatic beta cells in response to meals and reduce glucagon levels from alpha cells. This leads to better control of post-meal blood sugar spikes.
• Metformin Hydrochloride primarily acts by decreasing the amount of sugar produced by the liver and increasing the bodys sensitivity to insulin, allowing more glucose to be absorbed into the muscles and fat for energy use.
• Together, they effectively manage blood glucose levels throughout the day without causing significant hypoglycemia.

Directions for Use:

• Take ST-GLIPTIN M 100/500 exactly as prescribed by your doctor.
• It is usually taken once or twice daily with meals to reduce gastrointestinal side effects.
• Swallow the tablet whole with water. Do not crush or chew.
• Follow a consistent schedule for best results and maintain proper diet and exercise.
• Do not skip doses or stop the medication without consulting your physician.

Side Effects:

Like all medications, ST-GLIPTIN M 100/500 may cause side effects, although not everyone experiences them. Common and mild side effects include:

• Nausea
• Diarrhea
• Stomach upset or discomfort
• Headache
• Upper respiratory tract infections

Serious but rare side effects may include:

• Lactic acidosis (a medical emergency)
• Pancreatitis
• Allergic reactions such as rash, swelling, or itching
• Low blood sugar (especially if taken with other antidiabetics or alcohol)

Seek immediate medical attention if you notice symptoms like rapid breathing, muscle pain, dizziness, or persistent vomiting.