Rosuvastatin and Fenofibrate

About Rosuvastatin and Fenofibrate

ROUSTRIN F 20 is a potent combination medication designed to manage and treat hyperlipidemia and mixed dyslipidemia. It contains Rosuvastatin (20mg) and Fenofibrate (160mg), two powerful agents that work synergistically to reduce cholesterol and triglyceride levels. This dual-action approach not only lowers bad cholesterol (LDL) and triglycerides but also raises good cholesterol (HDL), thereby significantly reducing the risk of cardiovascular diseases.

Uses of ROUSTRIN F 20:

• Primary and secondary prevention of cardiovascular events in patients with high cholesterol and triglycerides.
• Treatment of hyperlipidemia and mixed dyslipidemia to reduce total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol.
• Adjunct to diet and other non-pharmacological treatments for lipid management.

Key Ingredients:

• Rosuvastatin (20mg): A statin that inhibits HMG-CoA reductase, an enzyme involved in cholesterol synthesis in the liver, thereby reducing cholesterol levels.
• Fenofibrate (160mg): A fibric acid derivative that activates peroxisome proliferator-activated receptors (PPARs), which increase the oxidation of fatty acids and decrease the production of triglycerides in the liver.

Key Benefits of ROUSTRIN F 20:

• Comprehensive Lipid Control: Effectively lowers LDL cholesterol and triglycerides while increasing HDL cholesterol.
• Cardiovascular Protection: Reduces the risk of heart attacks, strokes, and other cardiovascular events by improving lipid profiles.
• Dual Mechanism: Combines the benefits of a statin and a fibrate for a more effective approach to lipid management.
• Convenient Dosage: Simplifies treatment regimens by combining two lipid-lowering agents into a single tablet.

How Does It Work?

• Rosuvastatin: Works by inhibiting the enzyme HMG-CoA reductase in the liver, which is responsible for producing cholesterol. This inhibition leads to a reduction in LDL cholesterol and a modest increase in HDL cholesterol.
• Fenofibrate: Activates PPARs, which increase the oxidation of fatty acids and reduce the production and accumulation of triglycerides in the liver. This results in lower blood levels of triglycerides and a further increase in HDL cholesterol.

Side Effects:

• Common: Headache, dizziness, nausea, abdominal pain, constipation, and muscle pain.
• Serious: Muscle damage (rhabdomyolysis), liver enzyme abnormalities, and pancreatitis. Seek immediate medical attention if you experience unexplained muscle pain, weakness, or dark urine.

Safety Advice:

• Consult Your Doctor: Before starting ROUSTRIN F 20, inform your doctor about your complete medical history, especially any liver or kidney diseases.
• Regular Monitoring: Regular blood tests are necessary to monitor lipid levels, liver function, and kidney function.
• Avoid Alcohol: Limit alcohol consumption as it can increase the risk of liver problems.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy and breastfeeding. Discuss with your doctor if you are planning to conceive.
• Drug Interactions: Inform your doctor about all medications and supplements you are taking to avoid potential interactions.