Nintedanib Soft Gelatin capsules 150 mg

Product Description

NINTEPRIDE 150 is a prescription medication formulated with Nintedanib 150mg, designed primarily for the treatment of idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated interstitial lung disease (SSc-ILD), and other chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype. It helps in slowing down the decline of lung function and is a valuable therapy in the management of fibrotic lung disorders.

Key Ingredient:

Nintedanib (150mg)
Nintedanib is a tyrosine kinase inhibitor (TKI) that targets multiple growth factor receptors involved in the progression of lung fibrosis. It is an anti-fibrotic agent that interrupts signaling pathways that lead to scarring in lung tissue.

Key Benefits:

• Helps slow the progression of lung fibrosis in IPF and other chronic fibrosing ILDs.

• Supports better lung function over time in patients with progressive interstitial lung diseases.

• May reduce the rate of decline in forced vital capacity (FVC), a key measure of lung function.

• Offers a targeted therapeutic approach by inhibiting growth factor receptors involved in fibrosis.

• Improves quality of life by stabilizing respiratory symptoms in chronic pulmonary conditions.

How Does It Work?

NINTEPRIDE 150 works by inhibiting several receptor tyrosine kinases (RTKs), including platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), and vascular endothelial growth factor receptor (VEGFR). These receptors play a major role in the processes of fibrosis, including fibroblast proliferation and migration. By blocking these pathways, Nintedanib helps reduce the formation of scar tissue in the lungs, thus slowing disease progression in fibrotic lung conditions.

Directions for Use:

• NINTEPRIDE 150 should be taken orally with food to improve absorption and minimize gastrointestinal side effects.

• The usual dosage is one capsule (150mg) twice daily, approximately 12 hours apart.

• Do not crush, chew, or open the capsules; swallow them whole with water.

• Follow the dosage and administration schedule as prescribed by your healthcare provider.

• Do not adjust the dose or discontinue the medication without consulting your doctor.

Side Effects:

• Diarrhea is the most common side effect and may require dose adjustment or treatment.

• Nausea and vomiting, especially when taken on an empty stomach.

• Elevated liver enzymes, which may need regular monitoring.

• Loss of appetite and weight loss may occur with prolonged use.

• Headache, fatigue, and abdominal pain are also reported in some patients.

• In rare cases, it may cause bleeding complications or gastrointestinal perforation.

• Notify your healthcare provider immediately if you experience severe liver issues, persistent abdominal pain, or unusual bleeding.