Metformin Hydrochloride Prolonged-release 850 mg and Glimepiride IP 2 mg Tablets

Diabetes mellitus, especially Type 2 diabetes, is a growing health concern in India due to changing lifestyles, dietary habits, and reduced physical activity. Effective long-term blood sugar management often requires combination therapy that works through multiple mechanisms. SEIZMET G2 850 is a scientifically formulated oral antidiabetic medicine containing Metformin Hydrochloride Prolonged-Release 850 mg and Glimepiride IP 2 mg.
This combination helps achieve better glycaemic control while minimizing fluctuations in blood sugar levels. The prolonged-release form of metformin ensures sustained action throughout the day, making SEIZMET G2 850 a reliable choice for patients who need consistent diabetes management.

Uses

SEIZMET G2 850 is primarily prescribed for the management of Type 2 Diabetes Mellitus in adults when diet and exercise alone are not sufficient to control blood glucose levels. It is especially useful in patients who require dual therapy to manage fasting as well as post-meal blood sugar.
The medicine may be recommended for patients with insulin resistance, obesity-associated diabetes, or those who have not achieved adequate control with monotherapy.

Benefits

One of the key benefits of SEIZMET G2 850 is its dual mechanism of action. Metformin reduces glucose production in the liver and improves insulin sensitivity, while glimepiride stimulates insulin release from the pancreas.
The prolonged-release formulation of metformin helps reduce gastrointestinal discomfort and provides steady glucose control throughout the day.
Regular use, as advised by a doctor, can help lower HbA1c levels, reduce the risk of diabetes-related complications, and improve overall metabolic health. SEIZMET G2 850 also supports better weight management compared to some other antidiabetic therapies, making it suitable for long-term use.

Dosage

The dosage of SEIZMET G2 850 should be strictly followed as prescribed by a physician. Generally, it is taken once daily with or after meals to reduce the risk of stomach upset and hypoglycaemia.
The tablet should be swallowed whole and not crushed or chewed, as this may affect the prolonged-release mechanism. Dosage adjustments depend on individual blood sugar levels, kidney function, and treatment response. Regular monitoring of blood glucose is essential during therapy.

Side Effects

Like all medicines, SEIZMET G2 850 may cause some side effects, though not everyone experiences them. Common side effects include nausea, mild stomach upset, diarrhoea, headache, and dizziness.
In some cases, patients may experience low blood sugar levels, especially if meals are skipped or excessive physical activity is performed. Rare but serious side effects include lactic acidosis, particularly in patients with kidney or liver problems. Immediate medical attention is advised if symptoms such as extreme weakness, breathing difficulty, or unusual drowsiness occur.

Precautions and Warning

SEIZMET G2 850 should be used with caution in patients with kidney disease, liver disorders, heart conditions, or a history of alcohol abuse. It is not recommended for patients with Type 1 diabetes or diabetic ketoacidosis.
Alcohol consumption should be avoided during treatment, as it may increase the risk of hypoglycaemia and lactic acidosis. Pregnant and breastfeeding women should use this medicine only if clearly advised by a doctor. Regular monitoring of kidney function, liver enzymes, and blood sugar levels is essential during prolonged therapy.

Conclusion

SEIZMET G2 850 offers an effective and balanced approach to managing Type 2 diabetes by combining the benefits of metformin prolonged-release and glimepiride. Its sustained glucose-lowering action, improved tolerability, and proven efficacy make it a dependable choice for long-term diabetes care.
When used alongside a healthy diet, regular exercise, and medical supervision, SEIZMET G2 850 helps patients maintain stable blood sugar levels and improve their overall quality of life.