LETROZONE 2.5 is a pharmaceutical product containing the active ingredient letrozole 2.5 mg tablet, which is primarily used to manage hormone-sensitive breast cancer. This medication belongs to the class of aromatase inhibitors that reduce the production of estrogen, a hormone that can promote the growth of certain types of breast tumors. By inhibiting estrogen synthesis, LETROZONE 2.5 effectively slows down the progression of breast cancer and helps prevent its recurrence. It is mainly prescribed for women who have already stopped menstruating, also known as postmenopausal women, as these patients benefit significantly from estrogen reduction therapy.
LETROZONE 2.5 contains the active ingredient letrozole 2.5 mg tablet, a non-steroidal aromatase inhibitor. It works by blocking the enzyme aromatase, which converts androgens into estrogens in postmenopausal women. Since some breast cancers are estrogen-receptor positive, meaning they grow in response to estrogen, LETROZONE 2.5 helps reduce tumor size and prevents further cancer growth by lowering estrogen levels in the body.
LETROZONE 2.5 is used for:
Treatment of hormone receptor-positive breast cancer in postmenopausal women.
First-line treatment of advanced or metastatic breast cancer with hormone receptor-positive or unknown receptor status.
Extended adjuvant therapy after other treatments like tamoxifen to reduce cancer recurrence.
Prevention of breast cancer spread to other parts of the body in cases of advanced disease.
Occasionally used as initial treatment before surgery or when surgery is not suitable immediately.
Common side effects may include:
Hot flashes or flushing
Headaches and dizziness
Joint and muscle pain
Fatigue
Nausea
Increase in cholesterol levels
Weight gain and swelling
Increased sweating
Some patients may experience bone thinning (osteoporosis) with prolonged use, so monitoring bone density may be necessary. Serious allergic reactions are rare but require immediate medical attention.
Inform your doctor if you have any history of osteoporosis or bone fractures.
Let your healthcare provider know about any liver problems or cardiovascular conditions.
LETROZONE 2.5 is not indicated for use in premenopausal women or children.
If you experience tendon pain or swelling, contact your doctor right away as LETROZONE may cause tendon inflammation.
Use exactly as prescribed and do not discontinue without consulting your doctor.
Medications such as tamoxifen should generally not be taken with letrozole because tamoxifen can reduce letrozoles effectiveness.
Certain anti-inflammatory drugs and supplements may affect how LETROZONE 2.5 works, so always disclose all medications (prescription, OTC, herbal supplements) you are using to your healthcare provider.
Combined usage with aromatase inhibitors or estrogen-containing therapies is contraindicated.
LETROZONE 2.5, containing letrozole 2.5 mg tablet, is an essential medication for treating hormone receptor-positive breast cancer in postmenopausal women by significantly reducing estrogen levels. It slows the progression and recurrence of cancer with a well-established safety profile when used under medical supervision. Proper adherence to dosage, awareness of side effects, and consultation about drug interactions optimize its benefits for breast cancer management. This medicine is specifically designed to treat certain types of breast cancer in women who have already stopped menstruating (postmenopausal), offering targeted hormonal therapy that improves survival and quality of life.




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