Musculoskeletal pain and stiffness are among the most common health concerns faced by individuals of all age groups. Whether caused by physical strain, lifestyle factors, injuries, or chronic conditions, muscle spasms and discomfort can significantly affect daily activities and reduce overall quality of life. EPSTATE PLUS is a scientifically formulated combination medication that provides effective and comprehensive relief from muscle pain, stiffness, and spasms.
Each tablet of EPSTATE PLUS contains Eperisone (50 mg) and Paracetamol (325 mg). This unique blend offers a dual-action approachwhile Eperisone acts as a muscle relaxant to relieve stiffness and improve mobility, Paracetamol works as an analgesic and antipyretic to reduce pain and fever. Together, these two active ingredients provide rapid and long-lasting comfort, making EPSTATE PLUS a reliable solution for patients dealing with musculoskeletal conditions.
Eperisone Hydrochloride (50 mg): A centrally acting muscle relaxant that helps relieve muscle spasms, stiffness, and discomfort by improving blood circulation and reducing nerve excitability.
Paracetamol (325 mg): A widely used pain reliever and fever reducer that inhibits the synthesis of prostaglandins, the chemical mediators responsible for pain and inflammation.
This combination offers a synergistic effect where both ingredients complement each other to address muscle pain and associated symptoms effectively.
The therapeutic efficacy of EPSTATE PLUS is attributed to the dual mechanism of action of its ingredients:
Eperisone (Muscle Relaxant):
Acts on the central nervous system to reduce hyperactivity in spinal motor neurons.
Relieves muscle rigidity by decreasing excessive reflex activity.
Improves blood circulation in skeletal muscles, reducing stiffness and promoting relaxation.
Paracetamol (Analgesic & Antipyretic):
Inhibits cyclooxygenase (COX) enzymes in the brain, reducing prostaglandin synthesis.
Provides effective pain relief by lowering pain perception in the nervous system.
Reduces fever by acting on the hypothalamus to promote heat loss.
Together, this combination ensures comprehensive relief from pain, muscle stiffness, and inflammation, improving mobility and overall comfort.
Effective Muscle Relaxation: Relieves spasms and stiffness in muscles, allowing better movement.
Pain Management: Paracetamol offers rapid and reliable pain relief.
Reduced Inflammation: Helps decrease localized inflammation in muscles and joints.
Improved Mobility: Restores flexibility and enhances physical function.
Dual Action: Combines the strength of a muscle relaxant and an analgesic for holistic relief.
EPSTATE PLUS is commonly prescribed for conditions associated with musculoskeletal pain and spasm, including:
Acute and chronic back pain
Neck stiffness and cervical spondylosis
Lower back pain (lumbago)
Shoulder pain (periarthritis)
Muscle strain and sprain due to injury or overexertion
Fibromyalgia and nerve-related pain
Post-surgical musculoskeletal discomfort
Tension headaches linked with muscle stiffness
By addressing both pain and spasm, EPSTATE PLUS serves as an effective therapeutic option for patients requiring comprehensive management of muscle-related disorders.
Recommended Dose: 1 tablet two to three times daily, as prescribed by the healthcare provider.
Mode of Intake: Swallow the tablet whole with a glass of water. Do not chew or crush.
Timing: Best taken after meals to reduce gastrointestinal side effects.
Duration: Follow the prescribed course. Do not exceed the recommended dosage without consulting a doctor.
Like all medications, EPSTATE PLUS may cause some side effects, though not everyone experiences them.
Nausea
Dizziness
Headache
Stomach discomfort
Dry mouth
Fatigue
Allergic reactions (rash, itching, swelling, difficulty breathing)
Severe liver impairment (rare with long-term Paracetamol use)
Low blood pressure or muscle weakness (rare with Eperisone)
If any severe or persistent symptoms occur, patients should seek medical attention immediately.
Before starting EPSTATE PLUS, patients should keep the following precautions in mind:
Medical History: Inform your doctor if you have liver disease, kidney disease, or history of allergic reactions.
Pregnancy and Breastfeeding: Use only if prescribed by a healthcare professional.
Alcohol Consumption: Avoid alcohol, as it can increase the risk of liver damage from Paracetamol.
Driving and Operating Machinery: May cause dizzinessavoid activities that require alertness.
Hydration: Maintain adequate hydration to support drug metabolism and circulation.
EPSTATE PLUS may interact with other medications, including:
Other painkillers containing Paracetamol (risk of overdose)
Blood thinners (Warfarin, Aspirin) (increased risk of bleeding)
Alcohol and hepatotoxic drugs (higher risk of liver damage)
Muscle relaxants or sedatives (may enhance drowsiness)
Always inform your healthcare provider about all ongoing medications and supplements before starting EPSTATE PLUS.

Price:
Price 171.5 INR / Strip
Minimum Order Quantity : 1 Strip
Dosage Guidelines : Direction by physician
Storage Instructions : Cool and dry place
Physical Form : Tablets
Suitable For : Adults
Price 160 INR / Box
Minimum Order Quantity : 1 Box
Dosage Guidelines : Direction by physician
Storage Instructions : Cool and dry place
Physical Form : Tablets
Suitable For : Adults
Price 58.00 INR / Piece
Minimum Order Quantity : 1 Piece
Dosage Guidelines : As per suggestion
Storage Instructions : Cool & dry place
Physical Form : Tablets
Suitable For : Adults
Price 60.00 INR / Piece
Minimum Order Quantity : 1 Piece
Dosage Guidelines : As per suggestion
Storage Instructions : Cool & dry place
Physical Form : Tablets
Suitable For : Adults