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ATOVASTRIN EZ F is a triple-action lipid-lowering formulation that combines Atorvastatin Calcium, Fenofibrate, and Ezetimibe to provide comprehensive control over abnormal cholesterol and triglyceride levels. It is designed for individuals with mixed dyslipidemia, hypercholesterolemia, or those at high risk of cardiovascular diseases. This unique combination helps lower harmful lipids (LDL, triglycerides) and increase protective HDL cholesterol levels, reducing the overall risk of heart attack and stroke.
Atorvastatin Calcium (10 mg):
A statin that reduces the production of cholesterol in the liver, particularly lowering LDL (bad cholesterol) and total cholesterol, while modestly increasing HDL (good cholesterol).
Fenofibrate (160 mg):
A fibrate class drug that primarily targets elevated triglycerides and helps increase HDL levels, making it effective in treating mixed lipid disorders.
Ezetimibe IP (10 mg):
A cholesterol absorption inhibitor that blocks the absorption of dietary and biliary cholesterol in the intestine, helping further reduce total cholesterol and LDL-C.
Triple-action formula for comprehensive lipid control
Significantly reduces LDL-C, total cholesterol, and triglycerides
Increases HDL cholesterol to improve heart health
Helps manage mixed dyslipidemia and atherosclerotic risk
Reduces the likelihood of cardiovascular complications like heart attack and stroke
Convenient single-tablet therapy for better patient compliance
ATOVASTRIN EZ F works through three complementary mechanisms:
Atorvastatin inhibits HMG-CoA reductase, an enzyme involved in cholesterol synthesis in the liver. This reduces endogenous cholesterol levels and lowers LDL.
Fenofibrate activates peroxisome proliferator-activated receptors (PPARs), increasing the breakdown of triglyceride-rich particles and boosting HDL production.
Ezetimibe acts at the brush border of the small intestine to inhibit cholesterol absorption, reducing the amount of cholesterol entering the bloodstream from dietary sources.
Together, this combination offers synergistic lipid-lowering effects and improves the overall lipid profile more effectively than monotherapy.
Take ATOVASTRIN EZ F exactly as prescribed by your physician.
It is usually taken once daily, preferably after a meal.
Swallow the tablet whole with water; do not crush or chew.
Follow a low-fat, heart-healthy diet and regular exercise plan alongside medication.
Regular lipid profile monitoring is recommended to track progress.
Do not skip doses or stop the medication abruptly without consulting your doctor.
While generally well-tolerated, ATOVASTRIN EZ F may cause the following side effects in some patients:
Common Side Effects:
Headache
Muscle pain or weakness
Abdominal pain or indigestion
Diarrhea or nausea
Elevated liver enzymes (detected through lab tests)
Rare but Serious Side Effects:
Myopathy or rhabdomyolysis (severe muscle damage)
Pancreatitis
Liver dysfunction
Allergic reactions like rash, itching, or swelling
Seek immediate medical attention if you experience severe muscle pain, dark-colored urine, jaundice, or allergic reactions.
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