Apixaban 5mg Tablet

APIXAZEN 5, containing Apixaban 5 mg, is a prescription oral anticoagulant widely used to prevent and treat blood clots in patients with cardiovascular conditions. Belonging to the class of direct oral anticoagulants (DOACs), it provides a modern, convenient, and highly effective alternative to traditional anticoagulants like warfarin. By specifically targeting Factor Xa, a crucial enzyme in the clotting cascade, APIXAZEN 5 reduces the risk of serious complications such as stroke, deep vein thrombosis (DVT), and pulmonary embolism (PE).

This article provides a complete overview of Apixaban 5 mg, including its uses, mechanism of action, dosage, side effects, precautions, interactions, and why Steris Healthcare is a trusted name in delivering quality medicines like APIXAZEN 5.

What is Apixaban (APIXAZEN 5)?

Apixaban is a direct Factor Xa inhibitor marketed under the brand name APIXAZEN 5. It is prescribed to patients who are at risk of developing blood clots or who require long-term anticoagulation therapy. Unlike older blood thinners that require frequent monitoring and dietary restrictions, Apixaban offers predictable dosing, minimal interactions, and no need for routine INR monitoring, making it more patient-friendly.

It is especially valuable for patients with:

• Nonvalvular atrial fibrillation (NVAF) an irregular heart rhythm that increases stroke risk.
  
  

• Post-orthopedic surgery recovery where clot formation is a common complication.
  
  

• History of DVT or PE requiring long-term clot prevention therapy.
  
  

How Does APIXAZEN 5 Work?

Blood clotting is a natural process, but in some individuals, excessive clot formation can be dangerous. Apixaban works by targeting a specific step in the clotting cascade:

1. Factor Xa Inhibition Apixaban selectively inhibits Factor Xa, an enzyme required to convert prothrombin into thrombin.
   
   

2. Thrombin Reduction By reducing thrombin formation, the conversion of fibrinogen to fibrin (the structural component of blood clots) is minimized.
   
   

3. Lower Clot Formation This mechanism prevents harmful clot formation while still allowing normal clotting in cases of minor injuries.
   
   

The result is a balanced anticoagulant effect: effective prevention of dangerous clots, without overly suppressing the bodys natural defense against bleeding.

Uses of Apixaban 5 mg

APIXAZEN 5 is prescribed for a range of cardiovascular and clot-prevention purposes.

1. Stroke Prevention in Atrial Fibrillation (AF):
   
   

• Patients with nonvalvular atrial fibrillation are at significantly higher risk of stroke due to clot formation in the heart.
  
  

• Apixaban helps reduce this risk by keeping the blood thinner and less prone to clotting.
  
  

2. Treatment of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE):
   
   

• DVT occurs when blood clots form in the deep veins, usually in the legs.
  
  

• PE happens when these clots travel to the lungs, posing life-threatening risks.
  
  

• Apixaban treats both conditions and prevents recurrence.
  
  

3. Prevention of Post-Surgical Clots:
   
   

• After knee or hip replacement surgery, patients are prone to clot formation.
  
  

• Apixaban is prescribed to reduce the risk of post-operative DVT and PE.
  
  

4. Prevention of Recurrent Clots:
   
   

• In patients with a past history of DVT or PE, long-term therapy with Apixaban helps prevent relapses.
  
  

Dosage and Administration

• Strength Available: APIXAZEN 5 contains 5 mg of Apixaban per tablet.
  
  

• General Dosage:
  
  

• For stroke prevention in atrial fibrillation: 5 mg twice daily.
  
  

• For DVT/PE treatment: 10 mg twice daily for 7 days, followed by 5 mg twice daily.
  
  

• For post-surgical prevention: 2.5 mg twice daily, starting 1224 hours after surgery.
  
  

• Mode of Intake:
  
  

• Taken orally with or without food.
  
  

• Swallow whole with water.
  
  

• Missed Dose:
  
  

• Take as soon as remembered. If it is close to the next dose, skip the missed one and continue the regular schedule.
  
  

Note: Dosage may vary based on patients age, kidney/liver function, and doctors advice.

Side Effects of APIXAZEN 5

Like all medications, Apixaban may cause some side effects. These are usually manageable but can occasionally be serious.

Common Side Effects

• Bleeding (gums, nosebleeds, or minor cuts).
  
  

• Easy bruising.
  
  

• Mild nausea.
  
  

• Fatigue.
  
  

Less Common Side Effects

• Anemia (low red blood cell count).
  
  

• Skin rash or itching.
  
  

• Dizziness.
  
  

Serious Side Effects (Require Immediate Medical Attention)

• Severe bleeding (internal bleeding, blood in urine/stool, coughing blood).
  
  

• Allergic reactions (swelling of face/tongue, difficulty breathing).
  
  

• Liver problems (yellowing of eyes/skin, dark urine).

APIXAZEN 5 (Apixaban 5 mg) is a highly effective anticoagulant that plays a vital role in stroke prevention, clot management, and post-surgical recovery. Its targeted mechanism, predictable effects, and minimal monitoring requirements make it an advanced alternative to traditional anticoagulants.

With Steris Healthcares commitment to quality and affordability, APIXAZEN 5 is a reliable choice for both patients and healthcare professionals seeking safe and effective anticoagulation therapy.