FABRICAL ALPHA 0.5 is a highly effective medication designed to address deficiencies in calcium and phosphate metabolism. This prescription medication contains Alfacalcidol, a form of vitamin D used to treat conditions arising from low levels of calcium in the body. Alfacalcidol is particularly beneficial for patients with chronic kidney disease, hypoparathyroidism, and other conditions leading to impaired calcium metabolism. FABRICAL ALPHA 0.5 helps in the proper absorption and utilization of calcium and phosphate, ensuring optimal bone health and function.
Alfacalcidol, the active ingredient in FABRICAL ALPHA 0.5, is a prodrug that is converted in the liver to calcitriol, the active form of vitamin D3. Calcitriol binds to vitamin D receptors in various tissues, particularly in the intestines, bones, and kidneys. This binding enhances the absorption of calcium and phosphate from the intestines, reduces the excretion of calcium by the kidneys, and mobilizes calcium from bones. Together, these actions help maintain adequate calcium and phosphate levels in the bloodstream, essential for healthy bone formation and maintenance.
While FABRICAL ALPHA 0.5 is generally well-tolerated, some patients may experience side effects, including:





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